Postdoctoral fellowship

One postdoctoral fellowship is available in our group at IFOM, The AIRC Institute of Molecular Oncology located in Milan, Italy.

Our research:

Cancer cells are not invisible to the immune system, but many find ways to hide. Some exploit DNA damage response (DDR) pathways to suppress immune activation, while others accumulate mutations that reshape their interaction with immune cells. Understanding these mechanisms is critical for developing new therapies that enhance the immune system’s ability to target tumors.

The Leuzzi Lab investigates how DNA repair mechanisms and genome instability shape tumor-immune interactions, with the goal of uncovering novel strategies to enhance cancer immunotherapy. Our lab employs an interdisciplinary approach, combining CRISPR-based genome engineering, high-throughput functional genomics, multi-omics analyses, and in vivo models to dissect these critical processes.

The position:

We are seeking a highly motivated, curiosity-driven postdoctoral researcher to join our team. The successful candidate will thrive in our collaborative, international research environment, which offers access to cutting-edge technologies and strong institutional support.

What you will do:

-            Design and execute CRISPR-knockout (CRISPR-KO) and CRISPR-mediated base editing screens to investigate novel targets and biomarkers in cancer immunity.

-            Perform experimental approaches to study DDR and its role in tumor-immune interactions.

-            Generate, analyze, and interpret data to drive discovery and publications.

-            Collaborate with other laboratories.

-            Attend national and international meetings to present research findings

General requirements:

-            PhD in Molecular biology, Cancer biology, Genetics, or related area.

-            Documented experience in the DNA repair field.

-            Strong expertise in molecular and cell biology.

-            Strong publication record, including at least one publication within the last year in which the applicant is the principal author.

Position Details:

Competitive compensation package based on qualifications and experience, following institutional guidelines for postdoctoral researchers.

How to Apply:

Interested candidates should submit the following materials as a single PDF to Giuseppe Leuzzi at giuseppe.leuzzi@ifom.eu:

-   Curriculum vitae (CV)

-   Contact details for two references

-   Cover letter describing your previous research, your research interests, and motivation for joining our team.

Lab website: www.leuzzilab.com

We are excited to receive your application!